By Billy Hammond (Copyright AELS)

December 22, 2020

The mutant strain of SARS-CoV-2 named B.1.1.7 discovered in the UK is quite unusual. Up until recently, SARS-CoV-2 had been mutating at the rate of 1 to 2 mutations per month. B.1.1.7 shows 17 mutations!

According to this article, eight out of its seventeen mutations are those that encode the gene on the spike protein on the virus surface. One of them named N501Y increases the tightness of the binding to the ACE2 receptor, which is the pathway into human cells. The other, known as 69-70del, seems to cause the loss of two amino acids in the spike protein. What’s worrisome about this is that the lack of those two amino acids seems to have allowed viruses without them to elude the immune response in immunocompromised patients.

To make matters worse, a strain with a similar N501Y mutation has been discovered in South Africa and is being called 501Y.V2 in three provinces where cases are rising rapidly. Young people are also said to be suffering from more severe disease from it.

B.1.1.7: SARS-CoV-2変異株

SARS-CoV-2 (一般名:Covid-19)の変異ウイルス株 が英国で発見された。その変異株は B.1.1.7と名付けられた。ごく最近まで、 SARS-CoV-2から1ヶ月毎には1つか2つの変異株しか出ていなかったが、B.1.1.7には17変異が含まれている!

この記事によるとその17変異の内の8つはウイルス表面のスパイク タンパク質遺伝子をコードするものだ。その一つであるN501Yは人間細胞への道であるACE2レセプター(受容体 )との接続をより密接にする。その2つ目は 69-70delと呼ばれ、スパイクタンパク質の2つのアミノ酸を削除すると思われている。なぜこれが大きな問題だというのは、その2つのアミノ酸がない場合には免疫障害患者には免疫反応から隠れるような例がある。



English novels by Billy Hammond published by AELS



I. Majoh Gakuin and Hikari Juku – Japanese Witch Schools Trilogy

1. Majoh Gakuin & Hikari Juku – Japanese Witch Schools

2. Lost Witch (The second book)

3. Fate & Magic (The final book in the trilogy)

II. Brindle – Scryer Extraordinaire Trilogy

1. Brindle – Scryer Extraordinaire

2. Brindle – Scryer Extraordinaire – Returns

3. Brindle – Scryer Extraordinaire – Challenges (The final book in the trilogy)

III. Fantasy fiction set in Japan

1. 21st Century Ninja

2. Regressed

3. Japanese Woman

IV. Fantasy fiction set outside of Japan

1. Dimension Jumpers