By Billy Hammond (Copyright AELS)

December 5, 2019

If you drink a lot, then it’s important to know that ethanol (the main ingredient in alcoholic drinks) is an anti-vitamin, which inhibits the absorption of vitamin B1 (thiamine).

Thiamine is converted to TPP (thiamine pyrophosphate) in the body. The TPP serves as a co-enzyme in the decarboxylation of alpha ketoacids such as pyruvate and alpha-ketogluterate and in the use of pentose phosphates in the pentose phosphate pathway. The result is that the oxidation of alpha ketoacids is impaired. This creates disorders in the central and peripheral nervous systems as well as the cardiovascular system and can lead to beri-beri heart disease.

If you enjoy drinking a lot, then it’s probably a good idea to take a B1 supplement.

ビタミンB1とアルコール

アルコール飲料水が好きなら、酔わせてくれるエタノールは抗ビタミンと知るべき。エタノールはビタミンB1の吸収を抑制する。

B1は体内でTPP(チアミンピロリン酸)に変換される。TPPはピルビン酸塩やαケトグルタン酸のようなα-ケト酸の脱炭酸時にコエンザイムの役割を果たす。ペントースリン酸経路のペントースリン酸の利用にも活躍する。エタノールはα-ケト酸の酸化を妨害する。結果として中枢神経系・末梢神経系・心臓血管系の障害も可能となり、脚気心臓病ともつながる。

アルコールを沢山飲むなら、B1のサプリも飲んだ方がいい。

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English novels by Billy Hammond published by AELS

(AELS出版英語書籍リスト)

 

I. Majoh Gakuin and Hikari Juku – Japanese Witch Schools Trilogy

1. Majoh Gakuin & Hikari Juku – Japanese Witch Schools

2. Lost Witch (The second book)

3. Fate & Magic (The final book in the trilogy)

II. Brindle – Scryer Extraordinaire Trilogy

1. Brindle – Scryer Extraordinaire

2. Brindle – Scryer Extraordinaire – Returns

3. Brindle – Scryer Extraordinaire – Challenges (The final book in the trilogy)

III. Fantasy fiction set in Japan

1. 21st Century Ninja

2. Regressed

3. Japanese Woman

IV. Fantasy fiction set outside of Japan

1. Dimension Jumpers

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